Tadalafil...

[johnjuanb1]

Tadalafil is one of my favorite research liquid products. The size of my penis, both flaccid and erect is much larger in length and thickness for two days after dosing it. I love that you only have to dose tadalafil every other day to always be ready for better sex, with greater genital sensitivity and increased drive.

Another property that's awesome about tadalafil is the increased blood flow from vasodilation of the blood vessels which gives a killer pump in the gym. Everyone I have recommended using tadalafil preworkout has thanked me. Nobody believes generic cialis will give them a pump better than dbol until they try it for themselves. The pump is indescribable!

Originally, tadalafil was created for use in those with high blood pressure. This is a huge benefit in using tadalafil preworkout as it opens blood vessels thereby lowering blood pressure and protecting one from potential heart attack while training. In my 27 years of lifting weights I have come across several men who had a heart attack while squatting heavy and dead lifting heavy. Tadalafil could have possibly prevented their negative fate.

[Alternate-day oral tadalafil for erectile dysfunction with no successful intercourse at the baseline].

AuthorsDu Q, et al. Show all Journal
Zhonghua Nan Ke Xue. 2012 Jan;18(1):93-5. Article in Chinese.

Abstract

OBJECTIVE: To summarize the experience in the treatment of erectile dysfunction (ED) with no successful intercourse at the baseline with tadalafil.

METHODS: We retrospectively analyzed 21 cases of ED with no successful intercourse at the baseline treated with tadalafil on alternate days combined with sex guidance.

RESULTS: After 4 weeks of tadalafil treatment, 19 of the patients achieved successful sexual intercourse, and the IIEF-5 score was remarkably improved as compared with pre-medication (3.24 +/- 1.55 vs 18.95 +/- 3.02, P<0.0001). Mild adverse reactions were observed in 6 cases, including 2 cases of mild headache and 4 cases of facial blush.

CONCLUSION: Tadalafil on alternate days combined with sex guidance can significantly improve ED with no successful intercourse at the baseline.

 

[Elvia1023]

Tadalafil is incredible. I get no bad sides plus it remains active for so long. I have tried quite a few brands and most are crap. I used our one for the 1st time the other day and it wouldn't go down! Made up to find top class tadalafil but it's no surprise as everything I have tried of ours has been amazing. Balkan Cialis is top notch too. Literally all the others I have tried have been no where as good as those two.

 

[johnjuanb1]

Tadalafil is incredible. I get no bad sides plus it remains active for so long. I have tried quite a few brands and most are crap. I used our one for the 1st time the other day and it wouldn't go down! Made up to find top class tadalafil but it's no surprise as everything I have tried of ours has been amazing. Balkan Cialis is top notch too. Literally all the others I have tried have been no where as good as those two.

Ours is the best I've used out of half a dozen companies.

 

[Elvia1023]

Ours is the best I've used out of half a dozen companies.

Me too. I was genuinely made up as I have tried quite a few and been disappointed. It was just awkward every time I went to the toilet the day I tried it

 

[Knight9]

Viagra sucks...levitra is pretty awesome....avanafil is decent/good...but cialis/tadalafil is a beast and the clear winner in my mind.

Tadalafil and Dapoxitene make a hell of a combo.

Sent from my SM-N900V using Tapatalk

 

[Elvia1023]

Viagra sucks...levitra is pretty awesome....avanafil is decent/good...but cialis/tadalafil is a beast and the clear winner in my mind.

Tadalafil and Dapoxitene make a hell of a combo.

Sent from my SM-N900V using Tapatalk

I still haven't tried Levitra or Avanafil. Viagra gives me the worst headaches ever... 3 different brands. I have not used our Viagra but when you have Tadalafil/Cialis you don't need anything else!

 

[johnjuanb1]

Just got my tadalafil in the mail yesterday. Going to take a full pipette preworkout today, which is 1.5ml or 30mg. I sure have missed the tadalafil pumps in the gym. Can't wait!!!

 

[JonStrongbach]

I've seen some stuff here and there on guys using this as per workout and for the given reason. What do you recommend dosing EOD? I have not had good luck with cialis so far...had good luck with Viagra, shit works great with me, but it is not the most convenient thing...thoughts ?

 

[johnjuanb1]

I've seen some stuff here and there on guys using this as per workout and for the given reason. What do you recommend dosing EOD? I have not had good luck with cialis so far...had good luck with Viagra, shit works great with me, but it is not the most convenient thing...thoughts ?

I like 30mg-60mg eod. The pipette it comes with is 1.5ml so a full one is 30mg if it's from Superior. I have seen posts where guys get incredible pumps off 12.5mg.

 

[JonStrongbach]

Just thought of something I probably should have included in my last post - what is the reason behind dosing EOD as opposed to ED? I know with the exception of few things like HGH dosing more frequently seems to reduce unwanted side effects or at least simply maintain more stable levels in the body and just wanted a word on this.

 

[Elvia1023]

Just thought of something I probably should have included in my last post - what is the reason behind dosing EOD as opposed to ED? I know with the exception of few things like HGH dosing more frequently seems to reduce unwanted side effects or at least simply maintain more stable levels in the body and just wanted a word on this.

He dosed it that far apart for the simple fact it is active for so long. Tadalafil is active for over 1 day. For me it's effects seem to increase too. Plus when you wake up in the morning after using it the day before trust me you know about it!

You could dose it ed if you wanted. I know a lot of guys who do 10-25mg ed.

 

[mad mardigan]

Missed this sale buy minutes! Feckin central time!

 

[Knight9]

Just got my tadalafil in the mail yesterday. Going to take a full pipette preworkout today, which is 1.5ml or 30mg. I sure have missed the tadalafil pumps in the gym. Can't wait!!!

I don't see the point in doing it pre workout due to its onset. Do it 6 hrs prior or the night before.

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[johnjuanb1]

I don't see the point in doing it pre workout due to its onset. Do it 6 hrs prior or the night before.

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You're right. It shouldn't matter. It's just my OCD. Makes me feel better mentally taking it sublingually before training.

 

[johnjuanb1]

Missed this sale buy minutes! Feckin central time!

I just pm'd you. Will try to hook you up.

 

[johnjuanb1]

I don't know if it was the tadalafil or the melanotan II I took yesterday but something made me horny as a goat this morning to where I had to soank the monkey twice back to back this morning which is hardcore for a 45 year old. Hahaha

 

[johnjuanb1]

Tadalafil for the treatment of pulmonary arterial hypertension.

Authors
Klinger JR.
Journal
Expert Rev Respir Med. 2011 Jun;5(3):315-28. doi: 10.1586/ers.11.38.

Affiliation
Abstract
Tadalafil is a selective inhibitor of phosphodiesterase type-5 (PDE-5) that was originally developed for the treatment of male erectile dysfunction and recently approved for the treatment of pulmonary arterial hypertension (PAH). The antipulmonary hypertensive effects of nitric oxide and the natriuretic peptides are mediated via increasing intracellular cGMP and enzymatic degradation by PDE-5 is the major route of cGMP inactivation in the lung. Evidence is accruing that PDE-5 activity is increased in pulmonary vascular diseases and may contribute to the pathogenesis of PAH. The longer half-life of tadalafil allows for once-daily dosing as compared with three-times daily dosing for sildenafil, the only other PDE-5 inhibitor currently approved for treatment of PAH. This article reviews the role of cGMP and PDE-5 in PAH, presents the results of recent clinical trials and discusses the role of tadalafil in the treatment of this rare but difficult-to-treat disease.

 

[johnjuanb1]

Another all night erection thanks to tadalafil and melanotan II. Whoo hooo....

 

[johnjuanb1]

Tadalafil relieves lower urinary tract symptoms secondary to benign prostatic hyperplasia.

AuthorsMcVary KT, et al. Show all Journal
J Urol. 2007 Apr;177(4):1401-7.

Affiliation
Abstract
PURPOSE: We assessed the efficacy and safety of tadalafil dosed once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia.

MATERIALS AND METHODS: Following a 4-week, single-blind, placebo run-in 281 men were randomly assigned (1:1) to 5 mg tadalafil for 6 weeks, followed by dose escalation to 20 mg for 6 weeks or 12 weeks of placebo.

RESULTS: Tadalafil significantly improved the mean change from baseline in International Prostate Symptom Score at 6 weeks (5 mg tadalafil -2.8 vs placebo -1.2) and at 12 weeks (5/20 mg tadalafil -3.8 vs placebo -1.7). Larger changes were observed with inclusion of the placebo run-in at 12 weeks (5/20 mg tadalafil -7.1 vs placebo -4.5). Significant improvements were also seen in the International Prostate Symptom Score irritative and obstructive domains, the International Prostate Symptom Score quality of life index, a question about urinary symptom improvement and the Benign Prostatic Hyperplasia Impact Index (significant at 12 weeks) vs placebo. International Prostate Symptom Score and International Index of Erectile Function erectile function domain scores significantly improved in the 56% of men with lower urinary tract symptoms/benign prostatic hyperplasia who were sexually active and had erectile dysfunction. Changes in uroflowmetry parameters were similar in the placebo and tadalafil groups. Commonly reported (2% or greater) treatment emergent adverse events were "erection increased," dyspepsia, back pain, headache, nasopharyngitis and upper respiratory tract infection (each 5.1% or less). No change in post-void residual volume was seen with tadalafil treatment.

CONCLUSIONS: Tadalafil once daily was well tolerated and demonstrated clinically meaningful and statistically significant symptomatic improvement for lower urinary tract symptoms/benign prostatic hyperplasia. Tadalafil also improved erectile function in men with lower urinary tract symptoms and erectile dysfunction.

 

[johnjuanb1]

Tadalafil (Cialis) for men with erectile dysfunction.

AuthorsEardley I, et al. Show all Journal
Int J Clin Pract. 2002 May;56(4):300-4.

Affiliation
Comment in
Int J Clin Pract. 2002 May;56(4):236.
Abstract
Tadalafil is an inhibitor of phosphodiesterase type 5, and is currently undergoing regulatory review in the US and in Europe. Its chemical structure is significantly different from sildenafil, and in vitro studies confirm significant potency for PDE5 inhibition, with little activity against most of the other isoforms of the enzyme including PDE6, which is the isoform of the enzyme found within the retina. The half-life of tadalafil is 17.5 hours and clinical studies suggest significant activity 24 hours post-dosing. As with sildenafil, efficacy depends upon a normal sexual stimulus, and the drug can taken be as required. Tadalafil is effective in the treatment of men with erectile dysfunction, and it appears to have a relatively mild side-effect profile, with no visual side-effects noted.

PMID 12074215 [PubMed - indexed for MEDLINE]