T3 Overdose

[Virtuous]

Any chance it was peptide pros? I had the same thing with their T3, I grabbed some while waiting on a shipment from a vendor here (my fault, I didn’t time my order well) and it was significantly overdosed.

Took me almost a week to realize it, and from there I was weak/racing heart for another week or so until it calmed down.

Zero fun lol

 

[Muay Thai]

16 years into this scene you couldnt pay me to trust a research chemical liquid suspension, tablets or NO GO , HPLC, janoshik

 

[nothuman]

16 years into this scene you couldnt pay me to trust a research chemical liquid suspension, tablets or NO GO , HPLC, janoshik

Same. I would definitely not ever trust a liquid form of thyroid medication or anything for that matter.

 

[derzwerg]

Any chance it was peptide pros? I had the same thing with their T3, I grabbed some while waiting on a shipment from a vendor here (my fault, I didn’t time my order well) and it was significantly overdosed.

Took me almost a week to realize it, and from there I was weak/racing heart for another week or so until it calmed down.

Zero fun lol

Nah, MA Research.

Maybe I'll try it again with an oral syringe and starting way low but idk lol. Even if the dose was double the label I wouldn't have expected to have that sort of response.

Should have some from AA soon, probably just use that to hold me over until my international pack arrives.

 

[Virtuous]

Nah, MA Research.

Maybe I'll try it again with an oral syringe and starting way low but idk lol. Even if the dose was double the label I wouldn't have expected to have that sort of response.

Should have some from AA soon, probably just use that to hold me over until my international pack arrives.

Might be worth flagging this to Mike, he seems like the kind of guy who’d want know to fix it

 

[derzwerg]

Might be worth flagging this to Mike, he seems like the kind of guy who’d want know to fix it

Eh, I didn't intend to bring him into it on the board but it was guessed pretty quickly lol so whatever.

I emailed him on Sunday and haven't heard back yet.

 

[EnhancedFatGrappler]

Eh, I didn't intend to bring him into it on the board but it was guessed pretty quickly lol so whatever.

I emailed him on Sunday and haven't heard back yet.

The Problem is chemical in nature.

T3, or triiodothyronine, is a thyroid hormone that is not very water soluble. This means it has difficulty dissolving in water on its own. Even vigerously shaking it before consuming your dose will never lead to accurate dosing.

Care to guess why there is no liquid T3/T4 pharmaceutical product ;-)? Hint: It is lipid soluble.

Maybe @ickapeck can chime in with some more chemical knowledge.

You could make a solution, but it would need some more trickery to make it remain a stable solution. For examples, Liposomes are used for this (e.g. a lot of supplements use this, like Liposomal Glutathione or Liposomal Curcumin).

Bonus Question: Guess why research chems. don't use this method ;-)

 

[Doitagain]

The Problem is chemical in nature.

T3, or triiodothyronine, is a thyroid hormone that is not very water soluble. This means it has difficulty dissolving in water on its own. Even vigerously shaking it before consuming your dose will never lead to accurate dosing.

Care to guess why there is no liquid T3/T4 pharmaceutical product ;-)? Hint: It is lipid soluble.

Maybe @ickapeck can chime in with some more chemical knowledge.

You could make a solution, but it would need some more trickery to make it remain a stable solution. For examples, Liposomes are used for this (e.g. a lot of supplements use this, like Liposomal Glutathione or Liposomal Curcumin).

Bonus Question: Guess why research chems. don't use this method ;-)

In Europe there're pharmaceutical T3 and T4 products in liquid form...but they're NOT water based indeed.
They use Glycerol.

 

[nothuman]

The Problem is chemical in nature.

T3, or triiodothyronine, is a thyroid hormone that is not very water soluble. This means it has difficulty dissolving in water on its own. Even vigerously shaking it before consuming your dose will never lead to accurate dosing.

Care to guess why there is no liquid T3/T4 pharmaceutical product ;-)? Hint: It is lipid soluble.

Maybe @ickapeck can chime in with some more chemical knowledge.

You could make a solution, but it would need some more trickery to make it remain a stable solution. For examples, Liposomes are used for this (e.g. a lot of supplements use this, like Liposomal Glutathione or Liposomal Curcumin).

Bonus Question: Guess why research chems. don't use this method ;-)

And T3 is one of those things that really needs to be accurately dosed. Very low margin for error.

 

[VaginaBoob89]

I did not realize it was possible to “overdose” on t3

You realize pro BB’ers use upwards of 200mcg a day?

Personally I’ve used 125mcg a day weeks on end show prep

Never a problem at all and that was stacked with 200 mcg clen per day

Good luck to you and your health

Care to expand on this a bit? Why does everyone say "anything over 37.5mcg is going to eat your muscle and make you look worse"? Is there any truth to this?

 

[MackCoach]

Care to expand on this a bit? Why does everyone say "anything over 37.5mcg is going to eat your muscle and make you look worse"? Is there any truth to this?

Bro……
I’ve placed on the podium at NPC Nationals. 198 pounds on stage shredded.
Off season weight a lean 228.
So I’m gonna vote no …. I ran 125mcg t3 for 8+ weeks with Clen coming in to the show

Don’t be a fool and listen to all that pussy bro science and heresay

Get hardcore and push the envelope for yourself and see what happens

 

[SouthernMuscle]

The Problem is chemical in nature.

T3, or triiodothyronine, is a thyroid hormone that is not very water soluble. This means it has difficulty dissolving in water on its own. Even vigerously shaking it before consuming your dose will never lead to accurate dosing.

Care to guess why there is no liquid T3/T4 pharmaceutical product ;-)? Hint: It is lipid soluble.

Maybe @ickapeck can chime in with some more chemical knowledge.

You could make a solution, but it would need some more trickery to make it remain a stable solution. For examples, Liposomes are used for this (e.g. a lot of supplements use this, like Liposomal Glutathione or Liposomal Curcumin).

Bonus Question: Guess why research chems. don't use this method ;-)

Not sure why anyone would suspend ANYTHING in water or even think anyone else would.

Suspension Vehicles | SpecializedRx

SpecializedRx Products, LLC is an FDA registered pharmaceutical excipient manufacturer and repackager providing innovative products for the pharmacy, pharmaceutical, medical device, and related industries.

specializedrx.com

Take your pick. Suspend whatever you want, I’ve been doing it for years.

Doesn’t matter if the material is soluble or not. Its a suspension not a solution.

 

[Cerberus777]

Care to expand on this a bit? Why does everyone say "anything over 37.5mcg is going to eat your muscle and make you look worse"? Is there any truth to this?

If on enough gear and eating enough protein you'll be fine. Maybe a little flat over 50-75mcg. Everyone is different. I've gone as high as 200mcg (1mch per lbs) and didn't loose mucle.

 

[Unluckyscience]

It is soluble in DMSO and in 1M NaOH solution. If you freeze DMSO solution though it will participate. Take a look on t3 profile on sigma aldrich. The solution is used for cell cultures though

 

[BLKGUY2006]

Liquid is pretty much fool proof to dose, much more accurate then pills (unless pharm)

Did you just not feel anything from your 75mcg and up the dose till you did? To me that sounds more reasonable here.

Should be fine off one dose

I always felt the liquids that can affect HR like clen and T3 from a research site would be way to risky. With so many reputable sources on here why risk it?

 

[BLKGUY2006]

It takes a pretty decent laboratory to properly dose stuff in the micrograms range.
Speaking from direct, first hand experience in the manufacturing process.

This is exactly why I would be scared of anything that elevates heart rate from a research site. We talking MCG’s here.

 

[Muay Thai]

Care to expand on this a bit? Why does everyone say "anything over 37.5mcg is going to eat your muscle and make you look worse"? Is there any truth to this?

its CATABOLIC AF even with anabolics and androgens and peptides flowing. i have been on grams of gear and if you make one unconscious mistake regarding maintaining anabolism and not burning out CNS, excessive cardio, and I still looked flat af and fryed muscle, but I got dick skin conditioning everywhere, but it makes me feel like I'm on a super cut batch of coke msg+babylax goes right through me and makes me shake sitting profusely , 10x more than clen lol. t3 is such a nasty drug you couldn't pay me to use it, vicon keeps telling me I need to be running it with my 2-4iu gh but no way jose I'm getting peeled and feel great , I respond very poorly to stims!

 

[Muay Thai]

I always felt the liquids that can affect HR like clen and T3 from a research site would be way to risky. With so many reputable sources on here why risk it?

im right there with you g, its because people are cheap and cut corners. this is not something you want to cut corners or accidently overuse/overdue with, NOR DNP, NOR LETRO, NOR INSULIN etc

 

[VaginaBoob89]

its CATABOLIC AF even with anabolics and androgens and peptides flowing. i have been on grams of gear and if you make one unconscious mistake regarding maintaining anabolism and not burning out CNS, excessive cardio, and I still looked flat af and fryed muscle, but I got dick skin conditioning everywhere, but it makes me feel like I'm on a super cut batch of coke msg+babylax goes right through me and makes me shake sitting profusely , 10x more than clen lol. t3 is such a nasty drug you couldn't pay me to use it, vicon keeps telling me I need to be running it with my 2-4iu gh but no way jose I'm getting peeled and feel great , I respond very poorly to stims!

Yep... I've bumped to 75mcg and I'm feeling a bit cracked out and having sleeping difficulties. I was handling 25mcg t3 and 120 clen just fine so I think it's the t3, but maybe just lower bodyfat idk. Not particularly flat but I do feel hungry the morning after 1700g carb 250g protein 60g fat refeed days.

 

[BLKGUY2006]

im right there with you g, its because people are cheap and cut corners. this is not something you want to cut corners or accidently overuse/overdue with, NOR DNP, NOR LETRO, NOR INSULIN etc

Yup