doesn't it give you spontaneous erections as a side effect
Yes it can in many especially at higher doses. For me it's on par with cialis for sexual benefits if you dose it high enough. The combination of the two can be ridiculous. It's even been tested by ED sufferers in clinical studies.
Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study.
Wessells H1, Fuciarelli K, Hansen J, Hadley ME, Hruby VJ, Dorr R, Levine N.
1Department of Pharmacology, University of Arizona College of Medicine, Tucson, USA.
Abstract
PURPOSE:
We evaluated the erectogenic properties of a new cyclic alpha-melanocyte-stimulating hormone analogue, Melanotan-II, to treat men with psychogenic erectile dysfunction.
MATERIALS AND METHODS:
Ten men with erectile dysfunction of no known organic cause were entered in a double-blind, placebo controlled crossover study in which the erectogenic properties of Melanotan-II and a vehicle placebo were compared using real-time RigiScan monitoring. The presence, duration and rigidity of erections were recorded during a 6-hour period.
RESULTS:
In 8 of 10 men treated with Melanotan-II clinically apparent erections developed. Mean duration of tip rigidity greater than 80% was 38.0 minutes with Melanotan-II and 3.0 with placebo (p=0.0045). Transient side effects of nausea, stretching and yawning, and decreased appetite were reported more frequently after injections of Melanotan-II than placebo but none required treatment.
CONCLUSIONS:
Melanotan-II is a potent initiator of erections in men with psychogenic erectile dysfunction and has manageable side effects at a dose of 0.025 mg./kg.
PMID: 9679884
Another similar study...
Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II.
Wessells H1, Levine N, Hadley ME, Dorr R, Hruby V.
1Section of Urology, The University of Arizona College of Medicine, Tucson, 85724, USA.
[email protected]
Abstract
We review our experience with Melanotan II, a non-selective melanocortin receptor agonist, in human subjects with erectile dysfunction (ED). Melanotan II was administered to 20 men with psychogenic and organic ED using a double-blind placebo-controlled crossover design. Penile rigidity was monitored for 6 h using RigiScan. Level of sexual desire and side effects were reported with a questionnaire. In the absence of sexual stimulation, Melanotan II led to penile erection in 17 of 20 men. Subjects experienced a mean of 41 min Rigiscan tip rigidity>80%. Increased sexual desire was reported after 13/19 (68%) doses of Melanotan II vs 4/21 (19%) of placebo (P<0.01). Nausea and yawning were frequently reported side effects due to Melanotan II; at a dose of 0.025 mg/kg, 12.9% of subjects had severe nausea. We conclude that Melanotan II is a potent initiator of penile erection in men with erectile dysfunction. Our findings warrant further investigation of melanocortin agonists and antagonists on penile erection. International Journal of Impotence Research (2000) 12, Suppl 4, S74-S79.
PMID: 11035391