Since I've placed my first order for GH I thought that it'd be nice to learn a little more about hgh, igf-1 and the ideal level for fat-loss and small muscle building. My baseline igf-1 is around 230. I found very interesting studies and though about sharing them.
"Excessively low or high IGF-1 levels can lead to health problems like cancer and premature death."
*Chitnis MM, Yuen JS, Protheroe AS, et al. The type 1 insulin-like growth factor receptor pathway. Clin Cancer Res 2008,14:6364-6370.
*Werner H, Bruchim I. The insulin-like growth factor-I receptor as an oncogene. Arch Physiol Biochem 2009, 115:58-71.
*Davies M, Gupta S, Goldspink G, Winslet M. The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence. Int J Colorectal Dis 2006, 21:201-208.
*Sandhu MS, Dunger DB, Giovannucci EL. Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer. J Natl Cancer Inst 2002, 94:972-980.
*Kaaks R. Nutrition, insulin, IGF-1 metabolism and cancer risk: a summary of epidemiological evidence. Novartis Found Symp 2004, 262:247-260; discussion 260-268.
"A meta-analysis analyzed ten studies on IGF-1 levels and all-cause mortality. The authors found a “U-shaped” association, meaning that IGF-1 levels on the low end and the high end of the spectrum were associated with increased risk of premature death."
*Burgers AM, Biermasz NR, Schoones JW, et al. Meta-analysis and dose-response metaregression: circulating insulin-like growth factor I (IGF-I) and mortality. J Clin Endocrinol Metab 2011, 96:2912-2920.
Blah blah blah.
I wanna ask vets to chime in and guide please :headbang:
"Excessively low or high IGF-1 levels can lead to health problems like cancer and premature death."
*Chitnis MM, Yuen JS, Protheroe AS, et al. The type 1 insulin-like growth factor receptor pathway. Clin Cancer Res 2008,14:6364-6370.
*Werner H, Bruchim I. The insulin-like growth factor-I receptor as an oncogene. Arch Physiol Biochem 2009, 115:58-71.
*Davies M, Gupta S, Goldspink G, Winslet M. The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence. Int J Colorectal Dis 2006, 21:201-208.
*Sandhu MS, Dunger DB, Giovannucci EL. Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer. J Natl Cancer Inst 2002, 94:972-980.
*Kaaks R. Nutrition, insulin, IGF-1 metabolism and cancer risk: a summary of epidemiological evidence. Novartis Found Symp 2004, 262:247-260; discussion 260-268.
"A meta-analysis analyzed ten studies on IGF-1 levels and all-cause mortality. The authors found a “U-shaped” association, meaning that IGF-1 levels on the low end and the high end of the spectrum were associated with increased risk of premature death."
*Burgers AM, Biermasz NR, Schoones JW, et al. Meta-analysis and dose-response metaregression: circulating insulin-like growth factor I (IGF-I) and mortality. J Clin Endocrinol Metab 2011, 96:2912-2920.
Blah blah blah.
I wanna ask vets to chime in and guide please :headbang:
Last edited: